| How common is Avascular Necrosis? |
According to the American Academy of Orthopaedic Surgeons, 10,000 to 20,000 people in the United States alone develop Avascular Necrosis (or Osteonecrosis) each year, and most of them are between 20 and 50 years of age.[1] Also notable, AVN accounts for more than 10% of total hip replacement surgeries performed in the United States.[2]
A Japanese survey estimated 2500-3300 cases of AVN of the hip occur in Japan each year. This Japanese study estimates 34.7% of the national AVN cares were due to corticosteroid use, 21.8% to alcohol abuse, and 37.1% to idiopathic mechanisms.[3]
A study from France reported AVN in 4.3% of allogenic bone marrow transplant recipients.[4]
References
[1] "Osteonecrosis", National Institute of Arthritis and Musculoskeletal and Skin Diseases. Retrieved on 2009-04-10.
[2] Jeanne K Tofferi and William Gilliland. "Avascular Necrosis", emedicine. Retrieved on 2009-04-10.
[3] Ninomiya S. An epidemiological survey of idiopathic avascular necrosis of the femoral head in Japan. Annual Report of Japanese Investigation Committee for Intractable Disease. 1989.
[4] Lawson-Ayayi S, Bonnet F, Bernardin E, et al. Avascular necrosis in HIV-infected patients: a case-control study from the Aquitaine Cohort, 1997-2002, France. Clin Infect Dis. Apr 15 2005;40(8):1188-93. [Medline].


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